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Showing posts from June, 2017

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Mouse study suggests how hearing a warning sound turns into fearing it over time

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Fluorescent tagging shows the perineuronal nets (in red) surrounding neurons (in green) of mice. Emory researchers identified a role these nets play in "capturing" an auditory fear association. By Carol Clark The music from the movie �Jaws� is a sound that many people have learned to associate with a fear of sharks. Just hearing the music can cause the sensation of this fear to surface, but neuroscientists do not have a full understanding of how that process works. Now an adult mouse model reveals that changes in lattice-like structures in the brain known as perineuronal nets are necessary to �capture� an auditory fear association and �haul� it in as a longer-term memory. The journal Neuron published the findings by scientists at Emory University and McLean Hospital, a Harvard Medical School affiliate. The findings could aid research into how to help combat veterans suffering from post-traumatic stress disorder (PTSD). �We�ve identified a new mechanism � involving the regula...

Pollinator extinctions alter structure of ecological networks

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On the wings of National Pollinator Week, a new study by Emory biologist Berry Brosi gives insights into the dynamics of plant-pollinator interactions. By Carol Clark The absence of a single dominant bumblebee species from an ecosystem disrupts foraging patterns among a broad range of remaining pollinators in the system � from other bees to butterflies, beetles and more, field experiments show. Biology Letters published the research, which may have implications for the survival of both rare wild plants and major food crops as many pollinator species are in decline. �We see an ecological cascade of effects across the whole pollinator community, fundamentally changing the structure of plant-pollinator interaction networks,� says Berry Brosi , a biologist at Emory University and lead author of the study. �We can see this shift in who visits which plant even in pollinators that are not closely related to the bumblebee species that we remove from the system.�  If a single, dominant spe...

Mutant mosquitos make insecticide-resistance monitoring key to controlling Zika

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"You can't stop evolution," Emory disease ecologist Gonzalo Vazquez-Prokopec says, explaining that it is a natural process for mosquitos to mutate in response to insecticides. (CDC photo by James Gathany) By Carol Clark One of the most common insecticides used in the battle against the Aedes aegypti mosquito has no measurable impact when applied in communities where the mosquito has built up resistance to it, a study led by Emory University finds. The study is the first to show how vital insecticide-resistance monitoring is to control the Aedes mosquito � which carries the viruses that cause Zika, dengue fever and yellow fever. The journal PLoS Neglected Tropical Diseases published the research. �The results are striking,� says Gonzalo Vazquez-Prokopec , a disease ecologist at Emory and first author of the study. �If you use the insecticide deltamethrin in an area with high-deltamethrin resistance, it�s the same as if you didn�t spray at all. It does not kill the Aedes...

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To boldly go where public health hasn't gone before

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"Hopefully, Emory will make a mark in NASA history," says Yang Liu, associate professor of environmental health. (NASA photo) From Rollins Magazine Rollins School of Public Health researchers will soon take their research into orbit, partnering with the National Aeronautics and Space Administration (NASA) in a new satellite mission to study air pollution. NASA chose Rollins as a joint recipient of its $100 million award � $2.3 million of which will come to Rollins � to study the effects of air pollution on the population through a satellite mission, according to Yang Liu , associate professor of environmental health. He noted that this is the first time a NASA space mission has incorporated a public health component. "We're the scientific guinea pig," Liu said. The Rollins research group, led by Liu, co-created the project idea with NASA's Jet Propulsion Laboratory (JPL). The mission will construct and use a Multi-Angle Imager for Aerosols (MAIA) device to r...

A disarming comedian interviews an Emory psychologist loaded with facts about the brain

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Comedian Jordan Klepper, center, takes a break from filming in the Emory psychology department. He interviewed Emory psychologist Stephan Hamann, left, about the brain science involved in trying to understand the U.S. political divide and culture wars. (Photo by Carol Clark) By Carol Clark Why do some people have a liberal mindset while others seem set on conservatism? And what makes it so difficult to find common ground? Those are some of the questions explored in a one-hour special, � Jordan Klepper Solves Guns ,� which aired recently on Comedy Central. Comedian Jordan Klepper and a camera crew came to the Emory campus last October to film part of the program in the Department of Psychology. Klepper interviewed psychologist Stephan Hamann about his research into how the brain may influence whether people are on one end of the political spectrum or the other, and how we might use this knowledge to better understand one another.  �People develop their beliefs over a lifetime,� Ham...

The neuroscience of learning across borders

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Brains without borders: Emory Laney Graduate School student Charlie Ferris, from psychologist Stephan Hamann's lab, poses with a brain sculpture at the Institute of Neurobiology in Quer�taro, Mexico, during the recent Binational Mechanisms of Learning Forum. (Photo by COMEXUS)  By Carol Clark Jessica Dugan sits at a computer in the Emory University psychology department in Atlanta, training a rhesus monkey in a lab at a university in Quer�taro, Mexico, on the concept of transitive inference.  She watches the monkey in real-time on her screen. With a few clicks on her keyboard she can present the monkey with random images on a computer attached to its cage and see which image it chooses. The monkey is automatically rewarded with food pellets for correct choices. Eventually, the monkey begins to grasp that the computer �game� is based on a concept of transitive inference � the idea of a hierarchy based on a shared property. �It�s pretty cool,� Dugan says. �As long as there�s a ...

Students advocating for academic science

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PhD candidates Crystal Grant, left, and Joshua Lewis are vocal advocates for scientific research at universities, but neither is ready to commit to academic careers due to uncertainty about good jobs. Last summer, they made their case to congressional aides from the Georgia delegation. (Kay Hinton) By Hal Jacobs Emory Magazine Call it the 800-pound gorilla in the lab. Crystal Grant, a graduate student in Emory's Genetics and Molecular Biology program in the Graduate Division of Biological and Biomedical Sciences (GDBBS), faced it while studying how people�s DNA changes with age. Graduate student Joshua Lewis of the GDBBS Biochemistry, Cell and Developmental Biology program saw its shadow while researching how cells stick to neighbor cells� information that could lead to understanding how cancer cells metastasize. The problem weighed so heavily on Chelsey Ruppersburg, who graduated with a PhD in 2016, that she changed career directions after racing to earn a doctorate in cell biolog...

Key connection in neural code of 'love' uncovered in vole study

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New research probes the neural circuitry responsible for pair bonding in prairie voles. From Woodruff Health Sciences A team of neuroscientists from Emory University's Silvio O. Conte Center for Oxytocin and Social Cognition has discovered a key connection between areas of the adult female prairie vole's brain reward system that promotes the emergence of pair bonds. Results from this study, published this week in Nature , could help efforts to improve social abilities in human disorders with impaired social function, such as autism. This Conte Center study is the first to find the strength of communication between parts of a corticostriatal circuit in the brain predicts how quickly each female prairie vole becomes affiliative with her partner; prairie voles are socially monogamous and form lifelong bonds with their partners. Additionally, when researchers boosted the communication by using light pulses, the females increased their affiliation toward males, thus further demonst...

Georgia Climate Project creates state 'climate research roadmap'

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Environmental sciences instructor Daniel Rochberg, chief strategy officer for Climate@Emory , says the Georgia Climate Research Roadmap aims to create "Georgia's Top 40," a set of targeted research questions to help the state understand and address climate change. (Emory Photo/Video) By Kimber Williams Emory Report Scientists, researchers and environmental experts from across the state convened at Emory last week to draft the � Georgia Climate Research Roadmap � � a set of targeted research questions that could help Georgia better understand and address one of the century�s defining challenges. The goal of the May 22-23 gathering was to formulate �Georgia�s Top 40,� key climate research questions that could eventually aid decision-making and planning for Georgia policymakers, scientists, communities and service organizations. An initiative of the Georgia Climate Project , the roadmap was a response to the fact that communities across Georgia are already exploring strategi...